Open access
Oct 2026
Genetic encoding and mutagenesis of RNA droplet phenotypes
RNA droplets assembled from cotranscriptionally folded nanostructures have recently emerged as a promising platform for constructing protocells and minimal synthetic cell models. A custom-designed DNA template encodes an RNA nanostar that self-assembles into droplets by kissing-loop interactions. Here we show that su...
W. Verstraeten, Mai P. Tran, A. Taskina et al.
· Nature Chemical Engineering · 3 citations