DORAs produce dose-related improvements in insomnia sleep-related outcomes, with most effects plateauing within therapeutic ranges, consistent with a pharmacodynamic ceiling whereby sufficient attenuation of orexin-mediated arousal is achieved within approved dose ranges, limiting the value of further dose escalation.
Claudio Caiazza, L. Palagini, C. Toni et al.· Sleep Medicine· 0 citations
This study examined whether psychiatrists' routine prescribing decisions could be used to identify practice-grounded patterns supporting precision-oriented treatment selection, and found that similarity-based models may provide a more conceptually coherent approach.
Francesco Calabró, Claudio Caiazza, U. Albert et al.· European Neuropsychopharmaco...· 0 citations
Baseline neuroimaging may provide relevant prognostic information in Schizophrenia Spectrum, support that treatment response may be related to disturbances in large-scale network organization than to isolated structural abnormalities, and support the potential of prognostic neuroimaging in precision psychiatry and earl...
Claudio Caiazza, Giancarlo Fusco, L. Ugga et al.· European Archives of Psychia...· 0 citations
The Fusiform Gyrus appears to function as a dynamic, state-sensitive hub underlying perceptual, emotional, and cognitive disturbances in schizophrenia, in line with impaired ToM.
M. Ciccarelli, B. Mazza, A. Nasti et al.· Neuroscience and Biobehavior...· 0 citations
IVR-based cognitive rehabilitation appears feasible and tolerated in stable outpatients with schizophrenia, and the findings suggest improvement in psychomotor speed and modest improvement in negative symptoms.
Claudio Caiazza, Alessia Aletto, Luigi Franzese et al.· Schizophrenia Research: Cogn...· 0 citations
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