Clinton Ijirigho

Isoniazid impairs memory function in male Swiss mice by elevating pro-inflammatory cytokines and disruption of hippocampal, and prefrontal cortex neuronal morphology

Hibiscus sabdariffa ameliorates tramadol-induced neurotoxicity via antioxidant, anti-inflammatory, anti-apoptotic, and neurotransmission-regulating mechanisms

The misuse and abuse of tramadol, a synthetic opioid analgesic, has become a major public health concern in Africa. Although effective for managing moderate to severe pain, tramadol exposure has been associated with central nervous system toxicity. Hibiscus sabdariffa, commonly consumed as “Zobo,” contains bioactive su...