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Author

Colin Bonduelle

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Review Open access Sep 2026

Polyproline: A Synthetic Polypeptide With Unique Properties.

Polyproline is a unique polypeptide defined by its unusual conformational rigidity and physicochemical behavior. Addressing long-standing challenges in its synthesis and characterization, this mini-review highlights recent advances in the ring-opening polymerization of proline N-carboxyanhydride (NCA), enabling the con...

Rosanna Le Scouarnec, J. M. Galindo, Colin Bonduelle et al. · 0 citations
Sep 2026

Antibacterial Cyclic Oligo(disulfide)s with Tunable Hydrophilicity Dictate Membrane Interactions and Distinct Metabolic Interference

Using naturally occurring lipoic acid, cationic cyclic oligo(disulfide)s (CCOs) are designed that induce targeted membrane depolarization and trigger distinct downstream metabolic responses that represent a tunable antimicrobial system with considerable clinical translation potential.

Jia Guo, Si-Qi Zhang, Guang-Yuan Xu et al. · 0 citations
Open access Jul 2026

Click'n ROPISA: One-Pot Synthesis of Ultrabright Fluorescent Nanoparticles Made of Polypeptides.

Fluorescent nanoparticles are widely used in bioimaging and sensing, yet their preparation relies on multistep synthetic routes that limit scalability and structural control. Here we introduce a one-pot strategy that couples aqueous ring-opening polymerization-induced self-assembly (ROPISA) of γ-propargyl-L-glutamate N...

Amin El Jarroudi Hammou, Juliette Lavainne, Rohit Mangalwedhekar et al. · 0 citations

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