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Author

Colin R. Goding

2 papers indexed here

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Open access Sep 2026

Inflammatory macrophages promote metastatic potential in Triple-negative Breast Cancer through Integrated Stress Response signaling

The findings establish a macrophage-CXCL10-CXCR3-ISR signaling axis that fuels metastatic behavior in TNBC and identify this pathway as a potential node for therapeutic intervention.

Martina Crippa, Vincenzo Salemme, J. Chauhan et al. · 0 citations
Preprint Jul 2026

A quantitative model for the emergent population dynamics of the melanoma MITF rheostat

Cancer progression is driven by the ability of cells with identical driver mutations to adopt biologically distinct adaptive phenotypes. Yet the population dynamics implied by intratumour phenotypic heterogeneity is poorly understood. Melanoma is an excellent setting to study phenotype switching, in part because phenot...

Keith L. Chambers, Richard M. White, Colin R. Goding et al. · 0 citations

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