Open access
Aug 2026
Systems genetics analysis reveals immune mediators of coronavirus disease severity in mice
Abstract Severe disease following infection with SARS-CoV or SARS-CoV-2 is driven in part by genetically regulated immune responses that promote lung injury. To study genetic mechanisms of immune-mediated coronavirus pathogenesis, we screened the Collaborative Cross (CC) panel for Mus musculus strains that are phenotyp...
Ellen L. Risemberg, S. Leist, A. Schäfer et al.
· Genetics · 0 citations