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Sep 2026

Development and validation of a quantitative real-time PCR method for determination of residual host DNA in recombinant human C1 esterase inhibitor (rhC1INH).

A quantitative real-time polymerase chain reaction (qPCR)-based method was established and validated for the detection of residual host DNA in recombinant human C1 esterase inhibitor (rhC1INH), a biopharmaceutical produced in the mammary glands of transgenic rabbits. DNA was extracted from rhC1INH samples using a sodiu...

Cong Cong, Xiao-Ping Yu, Tian-Fei Du et al. · 0 citations

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