Bidirectional transitions between subjective cognitive decline and normal cognition and risk of mild cognitive impairment: A multistate Markov model study in NACC UDS.
BackgroundSubjective cognitive decline (SCD) may be an early indicator of Alzheimer's disease but often reverts to normal cognition (NC), leaving its prognostic significance uncertain.ObjectiveTo quantify bidirectional transitions between SCD and NC and to evaluate the long-term risk of progression to mild cognitive im...