Open access
Sep 2026
Structural basis for broad orthopoxvirus neutralization by two antibodies targeting distinct L1R epitopes
Two broadly neutralizing monoclonal antibodies, G4 and B9, that target the MPXV M1R protein, homologous to L1R in other OPXVs are presented, demonstrating cross-reactive binding and robust neutralization against multiple pathogenic OPXVs.
Li Chen, Guan-Ying Zhang, Hao-Tian Lin et al.
· Cell Reports Medicine · 0 citations