TAK1 Is Associated with Lipid-Induced Macrophage Polarization in Obesity Cardiomyopathy: Evidence from Network Pharmacology and Experimental Validation
Objective: To investigate whether TAK1 regulates lipid-induced macrophage polarization and contributes to inflammatory progression in obesity cardiomyopathy (OCM). Background: OCM is characterized by lipid overload, chronic low-grade inflammation, macrophage polarization imbalance, and myocardial remodeling. Preliminar...