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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Cong Xu

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2 papers indexed here

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Open access Oct 2026

Increased mitochondrial biogenesis by GPR56 contributes to venetoclax resistance in acute myeloid leukemia

Acute myeloid leukemia is a highly heterogeneous hematologic malignancy with an extremely poor prognosis. Although the BCL-2 inhibitor venetoclax introduced a new therapeutic option for patients, its widespread resistance substantially limited clinical application, and the underlying molecular mechanisms remained inc...

Yu-Sheng Luo, Xin He, Jun-Bin Huang et al. · 0 citations
Open access Oct 2026

Pharmacological inhibition of PRKDC-mediated DNA damage response by 3-hydroxyflavone selectively alleviates MLL-rearranged acute myeloid leukemia

Rearrangements of the mixed lineage leukemia (MLL) gene in acute myeloid leukemia (AML) have been associated with resistance to chemotherapy, and there is currently an unmet clinical need for effective targeted therapies. In this study, we performed high-throughput drug screening and identified 3-hydroxyflavone (3-...

Jing Liu, Chen-Xing Zhang, Min-Yi Zhao et al. · 0 citations

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