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Connor M. Kean

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Open access Oct 2026

Impact of aging on catecholaminergic ventricular arrhythmia and cardiac transcriptome of cardiac calsequestrin null mice

Catecholamine-induced polymorphic ventricular tachycardia (CPVT) is associated typically with mutations in Ryanodine Receptor type 2 (RYR2) and cardiac Calsequestrin (CASQ2) genes. RyR2 and CASQ2 along with membrane proteins, junctin and triadin, constitute the Ca2+ release unit in the junctional sarcoplasmic reticulum...

Connor M. Kean, Jacob A. Noeker, A. Shirali et al. · 0 citations

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