Review
Open access
Oct 2026
Stabilizing Functional Nucleic Acids for Real-Sample Diagnostics.
Functional nucleic acids (FNAs), including aptamers and DNAzymes, offer programmable recognition and catalysis for biosensing, but their performance in real samples is often compromised by nuclease degradation, matrix effects, and interface-associated losses. For diagnostic translation, stability must, therefore, be de...
Soyeon Lee, L. Dondi, Amal Mathai et al.
· Angewandte Chemie · 0 citations