Open access
Jul 2026
Imipridone treatment activates canonical NFkB and inflammatory signaling in THP1 differentiated macrophages 2258348
A link between a more immunologically active TME and response to ONC201 in patients with DMG is identified, and that changes in NFkB signaling occurred following imipridone treatment of the THP1 cell line.
Tyler Roady, Connor Purcell, Jillian Strandberg et al.
· Journal of Immunology · 0 citations