Review
Aug 2026
Immune surveillance and immune evasion of senescent cells.
Pau Garcia-Baucells, Manuel Serrano, Corina Amor
· Nature reviews. Immunology · 0 citations
3 papers indexed here
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Open access
Sep 2026
CAR T cell targeting of inflammatory myeloid progenitors in the bone marrow remodels border-associated macrophages and reverses cognitive aging
It is revealed that bone marrow myeloid progenitors harbor a heritable inflammatory transcriptional state that is transmitted to their BAM progeny, driving neuroinflammation and cognitive deterioration, and conserved in human aging.
Alexander S. Harris, James A. Rouse, Guang-Ran Guo et al.
· bioRxiv · 0 citations
Sep 2026
Aging rewires genetic dependencies in antitumor T cells.
The aged tumor microenvironment can impair antitumor T cell function, but the molecular regulators that become limiting in this setting remain poorly defined. In a recent issue of Cell, Chen and colleagues harness in vivo CRISPR screening to compare the effects of genetic perturbations in tumor-reactive CD8+ T cells ac...
Brian Oh, Corina Amor
· Cancer Research · 0 citations