Costel C. Darie

Bottlenecks in Proteomics: An Addendum.

Advances in peptidomics: analytical strategies and biological insights for clinical applications.

INTRODUCTION Endogenous peptides are emerging as key regulators of physiological and pathological processes and represent promising biomarkers and therapeutic targets. Advances in peptidomics have substantially improved their discovery and characterization, providing new insights into peptide biogenesis, biological fun...

MS-Based Proteomics Approach in Mapping Protein-Protein Interaction.

Exposomics: The Effect of Legacy Polychlorinated Biphenyls on the Proteome of Fish Consumers in the Great Lakes Region.

Sera from fish consumers in the Great Lakes basin were analyzed for legacy PCBs using isotope dilution mass spectrometry to determine if there were any correlations between protein dysregulations and high concentrations of PCBs in the sera.