Open access
Sep 2026
An RBP-J-heparan sulfate-dependent gatekeeper directs macrophage fate between inflammatory regulation and osteoclastogenesis
An RBP-J–Hs2st1–2-O-sulfated heparan sulfate (HS)–IFNβ dependent molecular network that acts as a gatekeeper balancing macrophage fate inclinations in response to TNF is identified.
Ting Zheng, Huan-Meng Hao, Jia-Lin Jiang et al.
· bioRxiv · 0 citations