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Author

Craig B. Wilen

2 papers indexed here

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Open access Aug 2026

Mucosal vaccine-elicited IgA is protective against zoonotic Betacoronavirus challenge

Current vaccines for respiratory viruses are primarily administered intramuscularly. Messenger RNA-lipid nanoparticle (LNP)-based intramuscular vaccination for respiratory coronaviruses induces strong systemic IgG antibody responses; they do not consistently elicit IgA in the upper and lower respiratory tracts. Using a...

Junghwa Seo, Emma Buck, Bryan Machani et al. · 0 citations
Open access Sep 2026

Aminopeptidase N is a receptor for hedgehog merbecoviruses.

Three coronavirus receptors from European hedgehogs are tested in cell-based assays and aminopeptidase N (APN) is identified as a receptor for hedgehog merbecoviruses, broadening understanding of receptor use across merbecoviruses and betacoronaviruses and inform risk assessments for viral emergence.

M. Jin, Victoria A. Jefferson, Zhe Zhao et al. · 1 citation

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