Author

Cristina Caraiman

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Open access Sep 2026

Scalable expansion of human iNKT cells: single-cell profiling and in vivo control of GvHD with preserved GvL activity

A scalable culture system to preferentially expand human CD4− iNKT cells directly from total peripheral blood mononuclear cells (PBMCs) using alpha-galactosylceramide (α-GalCer) and optimized cytokine conditions and IL-15 was the most effective cytokine.

Jordan Brouard, Cristina Caraiman, Ghislain Fievet et al. · bioRxiv · 0 citations