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Author

Cristina Sánchez Gutierrez

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Review Open access Sep 2026

Global seroprevalence of neutralizing and total antibodies against AAV vectors and their impact on the clinical gene therapy landscape: a scoping review

A scoping review of 50 studies published between 1968 and 2026 found AAV2, AAV8, and AAV5 were the most extensively studied serotypes and seroprevalence increased consistently with age and varied by geographic region, although the limited number of studies from Africa and Latin America precludes robust regional conclus...

Cristina Sánchez Gutierrez, Luisa Fernanda Bohorquez-Zambrano, Camila Garnica-Álvarez et al. · 0 citations

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