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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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Cristina Val

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Open access Aug 2026

Topliss‐Guided Optimization of Acetanilide‐Based Soluble Epoxide Hydrolase Inhibitors: Exploring the Pentafluorosulfanyl Group as a Potency‐Enhancing Motif

Surprisingly, substitution of the trifluoromethyl group of TPPU with a pentafluorosulfanyl substituent restored potency against human sEH, leading to the identification of a promising hit compound and the utility of the underexplored pentafluorosulfanyl group and the TBS strategy for optimizing amide‐based sEH inhibito...

Alba López-Ruiz, Eugènia Pujol, C. Ramos et al. · 0 citations

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