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Author

Cullen M. Taniguchi

2 papers indexed here

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Open access Sep 2026

Mitochondrial rewiring supports survival of triple negative breast cancer cells after ionizing radiation

Triple negative breast cancer (TNBC) is an aggressive disease with limited therapeutic options. Conventional treatments include neoadjuvant chemo-immunotherapy followed by surgical resection and may include further adjuvant immunotherapy and/or radiotherapy of the tumor bed and lymph nodes. Nonetheless, TNBC patients w...

Steven W. Wall, Karen Wang, A. Greer et al. · 0 citations
Sep 2026

Abstract B083: Mutant KRAS cooperates with the hypoxic tumor microenvironment to drive immunosuppressive macrophages via a paracrine PGE2/GM-CSF axis

Hypoxia is known to drive an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma (PDAC). However, the underlying immunosuppressive mechanisms remain unclear. Here, we hypothesized that hypoxia-induced factors secreted from tumor cells promoted immunosuppressive macrophages in PDAC. We tr...

Matthew T. Cribb, Ayeisha N. Colón-Ortiz, Sahar Fattani et al. · 0 citations

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