Author

D. Aguanno

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Open access Aug 2026

Systematic evaluation of PASEF acquisition strategies in complex metaproteomes

DIA- and Slice-PASEF show strong quantitative reproducibility, reduced ratio compression, and consistent species-abundance scaling, while functional profiling reveals expanded annotation depth, and the two highest-scoring methods, DIA- and Slice-PASEF, capture concordant host and microbial responses.

Feng Xian, Goran Mitulović, Ranjith Kumar Ravi Kumar et al. · Nature Communications · 0 citations