Evaluation of pro-inflammatory cytokines IL-15, IL-18, and IFN-γ as diagnostic biomarkers and their relationship with glycemic control in type 1 diabetes mellitus
Background. Type 1 diabetes mellitus (T1DM) is a persistent autoimmune condition marked by the T-cell-mediated obliteration of insulin-secreting pancreatic beta cells. This mechanism is governed by a complex network of pro-inflammatory cytokines that facilitate chronic inflammation and immune-mediated cell death. Compr...