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D. Aschmann

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Open access Oct 2026

Charge-Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti-Cancer Treatment.

Inorganic anticancer drugs such as cisplatin remain central to chemotherapy but are limited by poor tumor selectivity, rapid clearance, and off-target toxicity. We recently developed cationic Pt2L4 nanocages with 12-fold higher anticancer activity than cisplatin in PC-3M-Pro4 cells in vitro, but their positive charge c...

Renzo A. Knol, Bo-Chuan Hu, E. Bobylev et al. · 0 citations

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