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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

D. Bazou

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Open access Aug 2026

TP53 mutation drives unique transcriptional and functional vulnerabilities independent of del(17p) in multiple myeloma

This study integrates ex vivo drug sensitivity profiling, genomics, transcriptomics, and proteomics across 167 CD138+ bone marrow patient samples to characterize TP53-associated vulnerabilities and provides new insights into refining TP53 classification to optimize treatment strategies for high-risk MM.

D. Tsallos, N. Ikonen, Juho J Miettinen et al. · 0 citations

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