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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

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D. Chatterjee

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Open access Oct 2026

Solanum tuberosum peel extract attenuates acetaminophen-induced hepatotoxicity through modulation of inflammatory cytokines, apoptotic pathways, and CYP3A4 expression: evidence from molecular docking, Hep G2 cell assays, and an in ovo embryonic model

CYP3A4 is the primary cytochrome P450 that plays a secondary role along with CYP2E1 in the oxidation of acetaminophen (APAP) to the toxic metabolite N-acetyl-p-benzoquinone imine (NAPQI). APAP overdosing activates c-Jun N-terminal kinase (JNK), which activates the mitochondrial membrane permeability transition (MPT). T...

P. Goswami, D. Chatterjee, E. Fakola et al. · 0 citations

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