Open access
Sep 2026
Discovery of rare antigen-specific TCRs via replicate profiling
Development of effective vaccines and targeted immunotherapies for cancer, autoimmunity, allergy, and infectious diseases requires comprehensive understanding of functionality and antigenic specificity of involved T cell clones. A major technical challenge remains the high-throughput identification of antigen-speci...
E. Egorov, V. Kriukova, I. A. Shagina et al.
· Scientific Reports · 0 citations