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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

D. Cox

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Open access Sep 2026

Temporal Trajectories of the Tau Aggregate Interactome Reveal Stage‐Specific Vulnerabilities in Alzheimer's Disease

ABSTRACT Tau aggregation is a central pathological feature of Alzheimer's disease, yet how different forms of tau—ranging from monomers to small soluble aggregates and mature fibrils—interact with the cellular environment remains poorly understood. Here, we combine immunoaffinity proteomics with single‐molecule techniq...

Dorothea Boeken, Paula Beltran Lobo, Yun-Zhao Wu et al. · 0 citations
Open access Jul 2026

Direct single-molecule visualization of Hsp90-mediated relief of an Hsp70-folding block

HtpG reduces rebinding of DnaK to folding intermediates while still allowing engagement with misfolded clients, enabling productive refolding in the presence of typically inhibitory concentrations of DnaK and suggests that the number and position of DnaK binding sites on clients provide a mechanism by which proteins ca...

Nicholas R. Marzano, Bailey Skewes, Shannon McMahon et al. · 0 citations

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