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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

D. de Sancho

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Open access Sep 2026

Molecular basis of AMPA receptor labeling by ligand-directed acyl imidazole chemistry in living neurons

Rational design of covalent protein-labeling reagents in complex biological environments requires a molecular-level understanding of how the protein microenvironment governs chemical reactivity; yet, such mechanistic details remain inaccessible to experimental methods alone. In living neurons, Ligand-Directed Acyl Imid...

Dulce C. Guzmán-Ocampo, D. de Sancho, X. López · 0 citations
Open access Aug 2026

Switching Functional DNA-Binding Modes by Tuning Protein Order-Disorder Equilibria

A conserved sequence-ensemble-dynamics code in Nhp6A is revealed wherein not just stability, but also phosphorylation-induced conformational switching, disordered tail dynamics, and DNA binding-bending closely coordinate chromatin accessibility is revealed.

Shilpi Laha, H. Madhan, Yuji Itoh et al. · 0 citations

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