ABSTRACT Chlamydia trachomatis is an obligate intracellular pathogen that can reversibly halt replication and developmental transitions in response to immunological or pharmacological stress, a phenomenon linked to chlamydial persistence. Although polymorphic membrane proteins (Pmps) are known adhesins, their broader r...
Ailen N. Anna, M. Panzetta, Gloria N. Bettucci Ferrero et al.· Microbiology spectrum· 0 citations
Cell surface receptors are traditionally conceptualized as discrete molecular entities whose functional diversity arises primarily from gene expression and protein sequence variation. However, this view overlooks the extensive heterogeneity generated by post‐translational modifications, particularly glycosylation, whic...
María Payá-García, José Manuel Rojas-Marcos, I. A. Bermejo et al.· ChemBioChem· 0 citations
Post-translational modifications critically regulate extracellular molecular recognition, yet their roles in intrinsically disordered proteins remain poorly defined. Here, we integrate glycoproteomics, NMR, and cellular assays to reveal how glycosylation shapes the interaction network of osteopontin (OPN), a highly g...
I. A. Bermejo, D. del Balzo, M. Azkargorta et al.· JACS Au· 0 citations
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