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Author

D. Delitto

2 papers indexed here

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Jul 2026

Abstract PR004: A comprehensive pan-sarcoma single-cell transcriptomic meta-analysis reveals shared molecular programs across subtypes

Sarcomas are rare malignancies that encompass diverse histologic subtypes, despite their shared mesenchymal origins. Given their rarity, completing large-scale studies that aim to elucidate sarcoma biology and derive meaningful therapeutic advancements remains challenging. Identifying shared and distinct molecula...

Maria Korah, J. Agolia, R. Flojo et al. · 0 citations
Open access Jul 2026

AXL tyrosine kinase inhibition restores anti-PD-1 efficacy in melanoma through tumor-associated macrophage—dependent mechanisms 2255689

Immune checkpoint blockade (ICB) has transformed melanoma care, yet resistance is common and often driven by tumor-associated macrophages (TAMs). AXL, a Gas6-activated tyrosine kinase, is classically a tumor-intrinsic driver of invasion but is predominantly expressed by TAMs in melanoma, suggesting a role in regu...

Amanda R. Kirane, David Lee, Saurabh Sharma et al. · 0 citations

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