Open access
Aug 2026
Role of orphan G protein-coupled receptor GPR52 in breast cancer cell multicellular organization and collective invasion.
Loss of the orphan GPCR GPR52 in human breast cell lines leads to increased cell clustering, hybrid/partial EMT, and increased tumour burden in zebrafish, further expanding the understanding of mechanisms driving cancer progression and opening the door to novel therapeutic approaches.
Sarah Z. Hanif, Caleb Kutz, C. C. Au et al.
· British Journal of Cancer · 0 citations