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Author

D. Dick

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Open access Nov 2026

A phenome-wide association study of externalizing polygenic risk in the Adolescent Brain Cognitive Development (ABCD) study

Abstract Background Externalizing disorders encompass a range of disinhibited behaviors that typically manifest in youth and are linked with adverse psychological and social outcomes. Polygenic liability to externalizing behaviors has been associated with psychiatric and disease phenotypes in adults. Identifying correl...

S. Paul, Nathaniel S. Thomas, M. Choi et al. · 0 citations
Open access Oct 2026

Psychiatric and substance use disorder polygenic scores are associated with the exposome in youth.

Gene-environment correlations (rGE) present challenges for accurately estimating the individual and joint contributions of genetic and environmental influences on risk for psychiatric and substance use disorders. The present study examined rGE between polygenic risk scores (PGS) for psychiatric and substance use disord...

I-Tzu Hung, Nathaniel S. Thomas, D. Sosnowski et al. · 0 citations

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