Patient-reported outcome measures (PROMs) provide subjective information on symptoms, functional ability or quality of life. In post-COVID syndrome (PCS), lacking clear diagnostic criteria or biomarkers, PROMs enable a differentiated assessment of disease course and treatment effects. Within a multicenter research proj...
E. Hanc, Katharina Koller, R. Herold et al.· Health and Quality of Life O...· 0 citations
Persistent neurological symptoms are among the most disabling manifestations of post-COVID-19 syndrome (PCS), yet the contribution of ongoing CNS immune activation remains uncertain. CSF studies including clinically relevant COVID-19 recovered control cohorts are scarce. In this prospective single-center study, we enro...
D. Erhart, L. Balz, I. Giotaki et al.· medRxiv· 0 citations
Neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP), established biomarkers of neuroaxonal injury and astroglial pathology, are frequently only assessed in blood, which limits conclusions regarding their origin. Bi-compartmental analyses of CSF and serum may help differentiate central or peripher...
D. Erhart, B. Fazeli, F. Bachhuber et al.· Neurobiology of Disease· 0 citations
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