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D. Fayolle

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Open access Aug 2026

Rapid and accurate solubility determination of poorly soluble drug molecules by co-solvent extrapolation.

Aqueous solubility is a critical parameter in drug design. Common methods to measure solubility are often too slow or too inaccurate to be routinely used. Measuring very low solubilities (10-6 M and below) represents additional challenges. In this paper, we first describe a fast and reliable method to measure aqueous s...

D. Fayolle, Emilie M F Mwakondet, Marianne Carpentier et al. · 0 citations

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