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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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D. Flichman

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Open access Sep 2026

Core protein mutations are key determinants of hepatitis B virus replication during the hepatitis B e antigen-negative stage

Abstract The natural history of chronic hepatitis B virus (HBV) infection comprises distinct stages resulting from virus–host interactions. A late and pivotal event in this process is hepatitis B e antigen (HBeAg) seroconversion, marked by the abrogation of HBeAg expression, a significant reduction in viral load and th...

D. Flichman, María Cecilia García, Hugo Norberto Granchetti et al. · 0 citations

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