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Author

D. Hoffmann

2 papers indexed here

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Open access Oct 2026

Mocetinostat Shows Network-Inhibitory Effects on Glioblastoma Cells, Enhancing Radiotherapy Efficacy

Glioblastoma cells use neurite-like extensions, called tumor microtubes (TMs), as intercellular connections to integrate into a communicating network that contributes to glioblastoma’s high therapy resistance. Understanding the biological functions of tumor cell connectivity and overcoming network resistance has...

S. Heuer, D. Azorín, D. Hoffmann et al. · 0 citations
Open access Oct 2026

Glioblastoma immune landscape remodeling following treatment with CD70-targeted CAR-T cells

It is showcased that CD70-directed CAR-T cell therapy remodels the post-treatment immune landscape towards resolution of inflammation and reduced immunosuppression, supporting sustained immune surveillance.

A. Kourtesakis, D. Agardy, Clara Tejido Dierssen et al. · 0 citations

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