Background: Clinician-scientists translate clinical observation into discovery, trials, and policy, yet this workforce is shrinking across health systems worldwide. Integrated MB-PhD training, pausing medical training to complete a PhD before clinical exposure or specialisation, is one route into this career. We aimed...
D. Jafree, M. Sun, G. Stewart et al.· medRxiv· 0 citations
Spatial transcriptomics maps gene expression at cellular resolution, revealing how cells organize into multicellular niches. Yet computational analyses remain dataset-specific, without a transferable representation of tissue organization that generalizes across datasets, tasks and tissues or predicts how tissues behave...
Sebastian Birk, M. V. Sanian, Amirhossein Vahidi et al.· bioRxiv· 4 citations· ⚡1
An integrated single-cell RNA sequencing atlas across mouse models of PKD is constructed, mapping changes in cell type composition, gene expression, and intercellular signaling networks across the whole atlas and within individual models.
S. Miller, Hua Zhong, Weidong Wu et al.· JCI Insight· 0 citations
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