D. Jäger

T-Cell Receptor Single-Chain Antibody IgG1-Fc Fusion Proteins as Bispecific Engagers for Natural Killer and T Cells

Highlights What are the main findings? Novel trifunctional NK cell engagers have been developed that combine the ADCC-eliciting function of IgG1 Fc parts and NK cell-targeting mini antibodies with the capacity of T cell receptors to specifically recognize intracellular peptide antigens presented by MHC molecules Antibo...