Anti-PAR2 autoantibodies are associated with chronic histological injury in kidney transplant recipients
Introduction Non-HLA autoantibodies directed against G protein-coupled receptors (GPCRs) have emerged as potential contributors to endothelial activation, vascular injury, rejection, and chronic allograft dysfunction after kidney transplantation. Protease-activated receptors 1 and 2 (PAR1 and PAR2) are GPCRs located at...