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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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D. Jia

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Review Open access Aug 2026

Small-molecule inhibitors targeting the NLRP3 inflammasome: advances since mid-2023 and future perspectives.

The nod-like receptor protein 3 (NLRP3) inflammasome, a critical component of the innate immune system, governs the release of pro-inflammatory cytokines such as interleukin-1β (IL-1β) and IL-18 and thereby plays a central role in the pathogenesis of various inflammatory diseases. Its aberrant activation is closely lin...

D. Jia, Yun-Lei Hou, Yue Wu et al. · 0 citations

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