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Author

D. Joković

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2 papers indexed here

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Open access Aug 2026

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response

Cytochrome P450 2D6 (CYP2D6) is a polymorphic enzyme that influences antidepressant metabolism. This retrospective cohort study investigated the association between CYP2D6 genotype and treatment outcomes in 99 hospitalized patients with major depressive disorder (MDD) in Belgrade, Serbia. Patients were classified as po...

Aleksandra Petkovic-Curcin, A. Jeremić, D. Joković et al. · 0 citations
Open access Sep 2026

365. Association between CYP2D6 genotype and treatment outcomes in hospitalized patients with major depressive disorder: a retrospective cohort study

Abstract Background Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic hepatic enzyme involved in the metabolism of many commonly prescribed antidepressants. Genetic variations in CYP2D6 leads to differences in drug metabolism, affecting plasma concentrations and potentially influencing treatment effectiveness and to...

A. Jeremić, A. P. Curcin, D. Joković et al. · 0 citations

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