Next-generation hybrid bioanalytical platforms and clinical integration of TDM technologies for precision monitoring to optimize last-resort antibiotic therapy
Background The global rise of multidrug-resistant (MDR) infections has intensified the clinical reliance on last-resort antibiotics such as vancomycin, linezolid, and tigecycline, particularly in critically ill patients. These agents possess narrow therapeutic windows, complex pharmacokinetics, and substantial inter-pa...