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D. Klimpel

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Open access Oct 2026

Dose-dependent Effects of Cenobamate on Brivaracetam Pharmacokinetics: A Retrospective Cohort Study.

BACKGROUND Cenobamate is a novel antiseizure medication that inhibits cytochrome P450 2C19 (CYP2C19), which is involved in brivaracetam metabolism. Therefore, a pharmacokinetic interaction is assumed. In this study, the authors investigated the effects of cenobamate comedication on serum brivaracetam concentrations....

Eyad Hayani, A. Hagemann, D. Klimpel et al. · 0 citations

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