Author

D. Kukavica

2 papers indexed here

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Open access Sep 2026

Calpain-Dependent Protein Degradation Contributes to CASQ2-R33Q CPVT

Couplon protein loss in CPVT associated with CASQ2-R33Q is mediated by coordinated but distinct proteolytic pathways, with calpain-dependent TRDN degradation representing a key pathogenic event that promotes CASQ2 destabilization and arrhythmogenesis.

Laura Ramos-Hernández, D. J. Santiago, Rocío F. Serrano-Blanco et al. · Circulation Research · 0 citations

Open access Aug 2026

Ring-Like Scar Architecture and Arrhythmic Outcomes of Patients With Nondilated Left Ventricular Cardiomyopathy Treated With Ventricular Tachycardia Ablation.

BACKGROUND Nondilated left ventricular cardiomyopathy (NDLVC) is characterized by an elevated arrhythmic burden and frequent presence of ring-like late gadolinium enhancement (RL-LGE) pattern. However, the arrhythmic substrate and outcomes after ventricular tachycardia (VT) ablations remain undefined. OBJECTIVES This...

R. Pittorru, N. Pierucci, D. Kukavica et al. · JACC Clinical Electrophysiol... · 0 citations