Author

Dylan Leong

2 papers indexed here

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Open access Oct 2026

Epigenetic scores and aging clocks capture mortality risk in heart failure

Current prognostic tools for heart failure (HF) rely mainly on clinical parameters and often fail to reflect the biological heterogeneity underlying patient outcomes. DNA methylation (DNAm)-based aging clocks and trait-specific epigenetic scores capture biological age and cumulative lifestyle and environmental ex...

P. Meyre, M. Chong, P. Joseph et al. · European Heart Journal · 0 citations

PARTIAL ALTERNATIVE SPLICING IN CARRIERS OF DPYD rs75017182 EXPLAINS A MODEST ASSOCIATION WITH SEVERE

It is demonstrated that rs75017182‐ C promotes alternative splicing in the minigene plasmid model, and that the level of splicing may be affected by additional variants in linkage disequilibrium with rs75017182.

L. Hahn, Brianna M. Bembenek, Kelly J. Bouchonville et al. · 0 citations