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Open access Sep 2026

A detoxified E. coli heat-labile toxin LTh(αK) as a mucosal immunomodulator against acute respiratory viral infection: Proof-of-concept in a SARS-CoV-2 rodent model.

BACKGROUND Acute respiratory viral infections remain a global health burden, and current vaccines induce limited mucosal immunity at the respiratory epithelium. Host-directed strategies that strengthen innate mucosal responses may offer broader protection. LTh(αK), a genetically detoxified E. coli heat-labile toxin wit...

D. Lin, Fang-Ching Yeh, Ying-Shih Su et al. · 0 citations
Open access Aug 2026

Beyond Body Mass Index: Body Roundness Index, Inflammation, and Death.

BACKGROUND The body mass index (BMI) is widely used to assess obesity but fails to reflect fat distribution. The body roundness index (BRI) has been proposed as a better surrogate for central obesity, yet direct comparisons of their predictive power remain limited. METHODS We analyzed 341 336 adults from the Taiwan M...

D. Lin, S. Chua, Jen-Kuang Lee · 0 citations

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