Altered Expression of UFMylation Pathway Proteins Is Linked with Cancer Stem Cell Features and Aggressive Clinical Phenotype of Head and Neck Cancer
: Objectives: Head and neck squamous cell carcinoma (HNSCC), with oral squamous cell carcinoma (OSCC) comprising approximately 90% of cases, is a highly aggressive cancer characterized by frequent recurrence, therapy resistance, and poor prognosis, all largely attributed to the presence of cancer stem cells (CSCs). The...