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Author

D. N. Bhatt

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Review Open access Oct 2026

Gut epithelial barriers as regulators of metabolite-driven immune responses

Immunometabolism provides a framework for understanding how metabolic cues shape immune cell fate and function. While traditionally centered on cell-intrinsic pathways, emerging evidence highlights a critical role for epithelial barrier regulation in shaping immune responses by controlling exposure to microbiome derive...

Anuradha Tyagi, R. Tayal, D. N. Bhatt et al. · 0 citations
Open access Aug 2026

The CTCF Paralog BORIS Contributes to the Ovarian Cancer Transcriptional Program by Relaxing CTCF-mediated 3D Genome Organization

This work shows that the germline-specific CTCFL (BORIS) is aberrantly activated in high-grade serous ovarian carcinoma, where it remodels transcriptional, epigenetic, and three-dimensional genome organization by occupying CTCF-bound chromatin loop anchors and weakening CTCF-mediated chromatin insulation.

D. N. Bhatt, Arielle Scott, Ludmila Krymskaya et al. · 0 citations

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